Mei-Ling Ting Lee, PhD
Distinguished Professor in Biostatistics
and Computational Biology
Office Address:
Division of Biostatistics
B-122 Starling Loving Hall
320 West 10th Avenue
Columbus , Ohio 43210
Phone: (614) 293-3918
Send me an email
Education:
Ph.D. , Mathematics/Statistics, University of Pittsburgh , 1980
M.A., Mathematics/Statistics, University of Pittsburgh , 1978
M.S., Mathematics, National Tsing-Hua University , 1977
B.S., Mathematics , National Taiwan University, 1975
Appointments, awards and memberships:
Fellow, American Statistical Association
Fellow, Institute of Mathematical Statistics
Fellow, Royal Statistical Society
Elected member, International Statistical Institute
Mosteller Statistician of the Year, 2005 - American Statistical Association, Boston Chapter
Member, International Chinese Statistical Association
Member, International Biometrics Society (ENAR)
Member, International Society for Clinical Biostatistics
Member, International Society of Computational Biology
Member, American Public Health Association
Research:
Mei-Ling Ting Lee, Ph.D., is a biostatistician with a wide range of research interests in statistical modeling, methods and applications, including survival and time-to-event studies, latent disease progression, and nonparametric methods for clustered data. Her areas of medical application include cancer, occupational risk, the environment, epidemiology, microbiology, pharmacokinetics, genomics and proteomics. She was among the first to demonstrate the importance of replication in microarray studies and the need for assessing sample size and power for these kinds of studies. Dr. Lee is the founding editor and editor-in-chief of the international journal Lifetime Data Analysis, the only international statistical journal that is specialized in modeling time-to-event data.
Publications 2007:
LEE M-LT, Whitmore GA. Threshold regression for survival analysis: modeling event times by a stochastic process reaching a boundary. Statistical Sciences, 2006, 21: 501-513.
Rosner B, Glynn RJ, LEE M-LT, A Nonparametric Test for Observational Non-Normally Distributed Ophthalmic Data with Eye-Specific Exposures and Outcomes, Ophthalmic Epidemiology, 2007, 14: 243-250.
LEE M-LT, Whitmore GA, Laden F, Hart JE, Garshick E. A Case-Control Study Relating Railroad Worker Mortality to Diesel Exhaust Exposure Using a Threshold Regression Model, Journal of Statistical Planning and Inferences, (accepted, to appear).
LEE M-LT, Lifetime models and risk assessment, In: Encyclopedia of Quantitative Risk Assessments. Brian Everitt and Ed. Melnick, editors. Wiley (In press).
Zhang Y, Bertolino A, Fazio L, Blasi G, Rampino A, Romano R, LEE M-LT, Xiao T, Papp A, Wang D, and Sadée W, Novel polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory, Proceedings of the National Academy of Sciences, USA, 2007, 104: 20552-20557.
Publications 2006:
Rosner B, Glynn RJ, LEE M-LT, The Wilcoxon signed rank test for paired comparisons ofclustered data, Biometrics, 2006, 62:185-192.
Qin S, Qiu W, Ehrlich JR, Ferdinand AS, Richie JP, O’Leary MP, LEE M-LT, Liu BC-S. Development of a reverse capture autoantibody microarray for studies of antigen-autoantibody profiling, Proteomics, 2006, 6: 3199-3209.
Qiu W; LEE M-LT. A web-based calculator for sample-size and power calculations in microarray studies. Bioinformation. V1:2006. 251-252.
Rosner B; Glynn RJ; LEE M-LT. Extension of the Rank Sum Test for Clustered Data: two group comparisons with group membership defined at the subunit level. Biometrics. 62:2006. 1251-1259.
Mei-Ling Ting Lee and G.A. Whitmore. Threshold Regression for Survival Analysis: Modeling Event Times by a Stochastic Process Reaching a Boundry, Statistical Science, 2006, Vol. 21, No. 4, 501-513.
Books:
LEE M-LT. Analysis of Microarray Gene Expression Data, (2004), Kluwer Academic Publishers, Boston
Mesbah M, Cole BF, LEE M-LT, editors, Statistical Methods for Quality of Life Studies Design, Measurements and Analysis, (2002). Kluwer Academic Publishers, Dordrecht , The Netherland
Jewell NP, Kimber AC, LEE M-LT, Whitmore GA , editors, Lifetime Data: Models in Reliability and Survival Analysis, (1996). Kluwer Academic Publishers, Dordrecht , The Netherlands
