Mailing Address:
Division of Biostatistics
School of Public Health
The Ohio State University
B112 Starling-Loving Hall
320 West 10th Avenue
Columbus, OH 43210
Education:
Ph.D., Statistics, University of Wisconsin 2001
M.A., Mathematics, University of Wisconsin 1996
M.S., Computer Sciences, University of Wisconsin 1996
Appointments and memberships:
The International Biometric Society
American Statistical Association
Stromal gene expression during pulmonary sarcoidosis
Innate immunity: elucidation/modulation
Retrovirus models of lymphocyte transformation and disease
Genetic analysis of the breast tumor microenvironment
Integrating genomic and epigenomic alterations in cancer and its microenvironment
Courses Taught:
Design and Analysis of Studies in the Health Sciences II
Statistical methods for public health
Analysis of Longitudinal Data
Health data: sources and uses
Publications 2006:
Weber F, Shen L, Fukino K, Patocs A, Mutter GL, Galdes T and Eng C. “Total Genome Analysis of BRCA1/2-related Invasive Carcinomas of the Breast Identifies Tumor Stroma as Potential Landscaper for Neoplastic Initiation.” American Journal of Human Genetics, 2006, 78(6):961-972
Sarquis MS, Agrawal S, Shen L, Pilarski R, ZhouX-P and Eng C. “Distinct Expression Profiles for PTEN Transcript and Its Splice Variants in Cowden Syndrome and Bannayan-Riley-Ruvalcaba Syndrome.” The American Journal of Human Genetics, 2006, 79(1):23-30
Yu J, Wei M, Becknell B, Trotta R, Liu S, Boyd Z, Jaung MS, Blaser BW, Sun J, Benson DM Jr, Mao H, Yokohama A, Bhatt D, Shen L, Davuluri R, Weinstein M, Marcucci G, Caligiuri MA. "Pro- and antiinflammatory cytokine signaling: reciprocal antagonism regulates interferon-gamma production by human natural killer cells," Immunity, 2006, 24(5):575-90.
Crawford JR, Shen L, Stallones L, Koechlin K, Hayes J, Bean T and Wilkins JR “Using Participant Event Monitoring in a Cohort Study of Unintentional Injury among Children and Adolescents.” American Journal of Public Health, in press.
Publications 2005:
Wang, S., Shen, L., Carlton, P.S., Ang, E., Powolny, A.A., DeGroff, V.L., Clinton, S.K. (2005) Gene expression profiling of normal rat prostate tissue elucidates anit-carcinogenic mechanisms of dietary restriction. Abstract. AACR Meeting.
Sarquis MS, Weber F, Shen L, Borelsch CE, Jhiang SM, Zedenius J, Frilling A and Eng C. “High Frequency of Loss-of-heterozygosity in Imprinted Compared to Non-imprinted Genomic Regions in Follicular Thyroid Carcinomas and Atypical Adenomas.” The Journal of Clinical Endocrinology and Metabolism, 2005, 91(1):262-269
Weber F, Shen L, Aldred MA, Morrison CD, Frilling A, Saji M, Schuppert F, Broelsch CE, Ringel MD, Eng C. “Genetic classification of benign and malignant thyroid follicular neoplasia based on a 3-gene combination.” Journal of Clinical Endocrinology and Metabolism, 2005, 90(5):2512-2521
