My research focuses on using epidemiologic and animal models to investigate how cancer risk is modified by lifestyle. I am particularly interested in the effects of environmental exposures and dietary modifications on cancer risk. More specifically, I am interested in how early life exposures to these factors impacts adult cancer risk. My research uses population-based studies and animal models with the goal of moving between these two disciplines. Much of my research has focused on the impact of early nutrition and obesity on adult cancer risk, specifically breast and colon cancer. Another area of my research is on the impact of childhood secondhand smoke exposure on adult cancer risk and nicotine dependence. More recently, we have started research focusing on how occupational exposures among firefighters impacts cancer risk.
PhD, Tumor Biology, Georgetown University, 2004
MS, Cancer Biology, University of Texas M.D. Anderson Cancer Center, 2001
BS, Psychology, The College of William and Mary, 1993
2008 National Institutes of Health Fellows Award for Research Excellence
2007 American Association for Cancer Research Outstanding Clinical Scholar Award
2006 American Association for Cancer Research Scholar-in-Training Award
2003 American Association for Cancer Research Scholar-in-Training Award
2002 American Association for Cancer Research Scholar-in-Training Award
2002 American Association for Cancer Research Minority Scholar-in-Training Award
1999 American Association for Cancer Research Young Investigator’s Award
Khedher SB, Neri M, Papadopoulos A, Christiani DC, Diao N, Harris CC, Olivo-Marston S, Schwartz AG, Cote M, Koushik A, Siemiatycki J, Landi MT, Hung RJ, McLaughlin J, Duell EJ, Andrew AS, Orlow I, Park BJ, Brenner H, Saum K-U, Pesatori AC, Stücker I. Menstrual and reproductive factors and lung cancer risk: a pooled analysis from the International Lung Cancer consortium (ILCCO). International Journal of Cancer, 141(2): 309-323, 2017.
Fehringer G, Brenner DR, Zhang Z-F, Lee Y-CA, Matsuo K, Ito H, Lan Q, Vineis P, Johansson M, Overvad K, RIboli E, Trichopoulou A, Sacerdote C, Stucker I, Boffetta P, Brennan P, Christiani DC, Hong Y-C, Landi MT, Morgenstern H, Schwartz AG, Wenzlaff AS, Rennert G, McLaughlin JR, Harris CC, Olivo-Marston S, Orlow I, Park, BJ, Zauderer M, Barros Dios JM, Ruano Raviña A, Siemiatycki J, Koushik A, Lazarus P, Fernández‐ Somoano A, Tardon A, Le Marchand L, Brenner H, Saum K-U, Duell EJ, Andrew AS, Szeszenia‐ Dabrowska N, Lissowska J, Zaridze D, Rudnai P, Fabianova E, Mates D, Foretova L, Janout V, Bencko V, Holcatova I, Pesatori AC, Consonni D, Olsson A, Straif K, Hung RJ. Alcohol and Lung Cancer Risk Among Never Smokers: A Pooled Analysis from the International Lung Cancer Consortium and the SYNERGY Study. International Journal of Cancer, 140(9): 1976-1984, 2017.
Xu J, Galley J, Bailey M, Thomas-Ahner J, Clinton S, and Olivo-Marston SE. The Impact of Dietary Energy Intake Early in Life on the Colonic Microbiota of Adult Mice. Scientific Reports, 6:19083, 2016.
Olivo-Marston S.E., Hursting, S., Harris, C.C., and Lavigne, J. Effects of calorie restriction and diet-induced obesity on murine colon carcinogenesis, growth and inflammatory factors, and microRNA expression. PLoS One, 9 (4): e94765, 2014.
Olivo-Marston SE, Pennell M, DeGraffinreid C, Vitolins M, Bittoni M, Grainger E, Clinton S, and Paskett E. Weight Loss and Breast Cancer Biomarkers in a Randomized Dietary Trial Among Overweight/Obese Premenopausal Women. Jacobs Journal of Food and Nutrition, 1: 004, 2014.
McLaughlin JM, Olivo-Marston S, Vitolins MZ, Bittoni M, Reeves KW, Degraffinreid CR, Schwartz SJ, Clinton SK, Paskett ED. Effects of tomato- and soy-rich diets on the IGF-I hormonal network: a crossover study of postmenopausal women at high risk for breast cancer. Cancer Prev Res (Phila). 2011 May;4(5):702-10.
Olivo-Marston SE, Mechanic LE, Mollerup S, Bowman ED, Remaley AT, Forman MR, Skaug V, Zheng YL, Haugen A, Harris CC. Serum estrogen and tumor-positive estrogen receptor-alpha are strong prognostic classifiers of non-small-cell lung cancer survival in both men and women. Carcinogenesis. 2010 Oct;31(10):1778-86
Olivo-Marston S, Graubard BI, Visvanathan K, Forman MR. Gender specific differences in birthweight and the odds of puberty: NHANES III, 1988-1994. Paediatric and Perinatal Epidemiology, 24(3): 222-231, 2010.
Olivo-Marston S.E., Hursting, S., Perkins, S., Harris, C.C., Yakar, S., and Lavigne, J. Genetic reduction of IGF-1 inhibits colon tumorigenesis in azoxymethane-induced mice. Molecular Carcinogenesis. 48(12): 2009. 1071-1076.
Olivo-Marston, S.E., Yang, P., Mechanic, L.E., Bowman, E.D., Pine, S.R., Loffredo, C.A., Alberg, A.J., Caporaso, N.E., Shields, P.G., Chanock, S.J., Wu, Y., Jiang, R., Cunningham, J., Jen, J., and Harris, C.C. Childhood exposure to passive smoke and alterations in innate immunity increase adult lung cancer risk. Cancer Epidemiology, Biomarkers & Prevention. 18: 2009. 3375-3383.
Samet JM, Avila-Tang E, Boffetta P, Hannan LM, Olivo-Marston S, Thun MJ, Rudin CM. Lung cancer in never smokers: clinical epidemiology and environmental risk factors. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 15(18): 5626-5645, 2009.
Olivo-Marston, S.E., Zhu, Y., Lee, R.Y., Cabanes, A., Khan, G., Zwart, A., Wang, Y., Clarke, R., and Hilakivi-Clarke, L. Identification of gene signaling pathways mediating the opposite effects of prepubertal low and high fat n-3 PUFA diets on breast cancer risk. Cancer Prevention Research, 1: 532-545, 2008.