Assistant Professor - Practice
Environmental Health Sciences
Phone:
614-247-7682
Email:
song.991@osu.edu
1841 Neil Ave.
380C Cunz Hall
Columbus, OH 43210
Background:
Dr. Song received her master’s degree in molecular genetics and Ph.D. in cancer epigenetics and completed her postdoctoral training in the field of molecular epidemiology in cancer research, particularly cancer prevention and tobacco regulatory sciences. Her research interests focus on multi-omics studies to integrate environmental/lifestyle factors, epigenetics, genetics, and biomarkers of exposure to understand how differences among genes and environments aid to identify biomarkers of effects and ultimately control and prevent disease. Current research includes tobacco use, diet, and obesity.
Dr. Song is the Principal Investigator on a 2015-2017 OSU-CERTS Pilot Project ($100K): Effects of Electronic Cigarette Use on the Human Lung.
Research Interests:
Epigenetics, Biomarkers of Exposure, Cancer Risk Factors, Gene-Environment Interactions, Molecular Epidemiology, Tobacco, Cancer Prevention, Cancer, Molecular Carcinogenesis, and Multi-Omics Data
Education:
Postdoctoral fellowship in Cancer Prevention/Tobacco Regulatory Sciences, The Ohio State University, 2014-18
PhD, Cancer Epigenetics, University of Hawaii at Manoa, 2014
MSc, Molecular Genetics, CHA University College of Medicine, Korea, 2006
BSc, Biology, Sungshin Women’s University, Korea, 2004
Awards/Honors:
2017 Publication of the year (1st Place), The Ohio State University Comprehensive Cancer Center
2017 RMATRIX-II Collaboration Pilot Award, University of Hawaii
2017 Research Award, Prevent Cancer Foundation
2015 Center of Excellence in Regulatory Tobacco Science Pilot Award, The Ohio State University
2014 FDA Tobacco Regulatory Science Fellowship
2012 Weinman Innovator Award, University of Hawaii Foundation
Selected Publications:
2017
- Song MA, Brasky TM, Weng DY, McElroy JP, Marian C, Higgins MJ, Ambrosone C, Spear SL, Llanos AA, Kallakury BV, Freudenheim JL, Shields PG. Landscape of genome-wide age-related DNA methylation in breast tissue. Oncotarget. 2017, PMID: 29383109 [PMCID: PMC5777721] (Invited Research Paper)
- Shields PG, Berman M. Brasky TM, Freudenheim JL, Mathe EA, McElroy J, Song MA, Wewers MD. A Review of Pulmonary Toxicity of Electronic Cigarettes In The Context of Smoking: A Focus On Inflammation. Cancer Epidemiol Biomarkers Prev. 2017, PMID: 28642230 [PMCID: PMC5614602]
- Song MA, Benowitz NL, Berman M, Brasky TM, Cummings KM, Hatsukami D, Marian C, O’Connor R, Rees V, Woroszylo C, Shields PG. Cigarette filter ventilation and its relationship to increasing rates of lung adenocarcinoma. J Natl Cancer Inst, 2017, PMID: 28525914
2016
- Song MA, Kwee SA, Tiirikainen M, Hernandez BY, Okimoto G, Tsai NC, Wong LL, Yu H. Comparison of genome-scale DNA methylation profiles in hepatocellular carcinoma by viral status. Epigenetics. 2016, PMID: 27248055, [PMCID: PMC4939927]
- Song MA, Brasky TM, Marian C, Weng DY, Taslim C, Llanos AA, Dumitrescu RG, Liu Z, Mason JB, Spear SL, Kallakury BV, Freudenheim JL, Shields PG. Genetic variation in one-carbon metabolism in relation to genome-wide DNA methylation in breast tissue from healthy women. Carcinogenesis. 2016, PMID: 26961134
- Song MA, Marian C, Brasky TM, Reisinger S, Djordjevic M, Shields PG. Chemical and Toxicological Characteristics of Conventional and Low-TSNA Moist Snuff Tobacco Products. Toxicol Lett. 2016, PMID: 26802282, [PMCID: PMC4910161]
2015
- Song MA, Brasky TM, Marian C, Weng DY, Taslim C, Dumitrescu RG, Llanos AA, Freudenheim JL, Shields PG. Racial differences in genome-wide methylation profiling and gene expression in breast tissues from healthy women. Epigenetics. 2015, PMID: 26680018, [PMCID: PMC4844220]
- Ching T†, Ha J†, Song MA, Tiirikainen M, Molnar J, Berry MJ, Towner D, Garmire LX. Genome-scale hypomethylation in the cord blood DNAs associated with early onset preeclampsia. †Equal contributors. Clin Epigenetics. 2015.PMID: 25806090, [PMCID: PMC4371797]
- Shvetsov YB, Song MA, Cai Q, Tiirikainen M, Xiang YB, Shu XO, Yu H. Intra-individual variation and short-term temporal trend in DNA methylation of human blood. Cancer Epidemiol Biomarkers Prev. 2015, PMID: 25538225, [PMCID: PMC4355238]
2014
- Ching T, Song MA, Tiirikainen M, Molnar J, Berry M, Towner D, Garmire LX. Genome-wide hypermethylation coupled with promoter hypomethylation in the chorioamniotic membranes of early onset pre-eclampsia. Mol Hum Reprod. 2014, PMID: 24944161, [PMCID: PMC4131767]
2013
- Ling H, Spizzo R, Atlasi Y, Nicoloso M, Shimizu M, Redis RS, Nishida N, Gafà R, Song J, Guo Z, Ivan C, Barbarotto E, De Vries I, Zhang X, Ferracin M, Churchman M, van Galen JF, Beverloo BH, Shariati M, Haderk F, Estecio MR, Garcia-Manero G, Patijn GA, Gotley DC, Bhardwaj V, Shureiqi I, Sen S, Multani AS, Welsh J, Yamamoto K, Taniguchi I, Song MA, Gallinger S, Casey G, Thibodeau SN, Le Marchand L, Tiirikainen M, Mani SA, Zhang W, Davuluri RV, Mimori K, Mori M, Sieuwerts AM, Martens JW, Tomlinson I, Negrini M, Berindan-Neagoe I, Foekens JA, Hamilton SR, Lanza G, Kopetz S, Fodde R, Calin GA. CCAT2, a novel non-coding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer. Genome Res. 2013, PMID: 23796952, [PMCID: PMC3759721]
- Song MA, Tiirikainen M, Kwee SA, Okimoto G, Yu H, Wong LL. Elucidating the Landscape of Aberrant DNA Methylation in Hepatocellular Carcinoma. PLoS One. 2013, PMID: 23437062, [PMCID: PMC3577824]
2012
- Kwee S, Song MA, Cheng I, Loo LW, Tiirikainen M. Measurement of Circulating Cell-free DNA in Relation to 18F-fluorocholine PET/CT Imaging in Chemotherapy-Treated Advanced Prostate Cancer. Clin Transl Sci. 2012, PMID: 22376260, [PMCID: PMC3500883]
Book Chapters
- Unhee Lim and Min-Ae Song, Dietary and Lifestyle Correlates of DNA Methylation, Methods in Molecular Biology in Cancer Epigenetics, Springer Science (Human Press). Methods Mol Biol. 2012;863:359-76. PMID: 22359306 (Invited Chapter)
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