Qinghua Sun, MD, PhD

Brook RD, Sun Z, Brook JR, Zhao X, Ruan Y, Yan J, Mukherjee B, Rao X, Duan F, Sun L, Liang R, Lian H, Zhang S, Fang Q, Gu D, Sun Q, Fan Z, Rajagopalan S. Extreme Air Pollution Conditions Adversely Affect Blood Pressure and Insulin Resistance: The Air Pollution and Cardiometabolic Disease Study. Hypertension. 2015 Nov 16. [Epub ahead of print]

 

Yang J, Yin P, Zhou M, Ou CQ, Guo Y, Gasparrini A, Liu Y, Yue Y, Gu S, Sang S, Luan G, Sun Q, Liu Q. Cardiovascular mortality risk attributable to ambient temperature in China. Heart. 2015;101:1966-72

 

Liu C, Yavar Z, Sun Q. Cardiovascular Response to Thermoregulatory Challenges. Am J Physiol Heart Circ Physiol. 2015 Oct 2 [Epub ahead of print]

 

Wang T, Liu C, Wang A, Sun Q. Intermittent cold exposure improves glucose homeostasis associated with brown and white adipose tissues in mice. Life Sci. 2015;139: 153–159

 

Zheng Z, Zhang X, Wang J, Dandeka A, Kim H, Qiu Y, Xu X, Cui Y, Wang A, Chen LC, Rajagopalan S, Sun Q, Zhang K. Exposure to Fine Airborne Particulate Matters Induces Hepatic Fibrosis in Murine Models. J Hepatol. 2015; 63:1397-404.

 

Hogan MK, Kovalycsik T, Sun Q, Rajagopalan S, Nelson RJ. Combined Effects of Exposure to Dim Light at Night and Fine Particulate Matter on C3H/HeNHsd Mice. Behav Brain Res. 2015;294:81-88

 

Bai Y, Xu Z, Lu B, Sun Q, Tang W, Liu X, Yang W, Xu X, Liu Q. Effects of Climate and Rodent Factors on Hemorrhagic Fever with Renal Syndrome in Chongqing, China, 1997-2008. PLoS One. 2015;10:e0133218

 

Ying Z, Xie X, Bai Y, Chen M, Wang X, Zhang X, Morishita M, Sun Q, Rajagopalan S. Exposure to concentrated ambient particulate matter induces reversible increase of heart weight in spontaneously hypertensive rats. Part Fibre Toxicol. 2015;12(1):15

 

Cui Y, Jia F, He J, Xie X, Li Z, Fu M, Hao H, Liu Y, Liu DZ, Cowan PJ, Zhu H, Sun Q, Liu Z. Ambient Fine Particulate Matter Suppresses In Vivo Proliferation of Bone Marrow Stem Cells through Reactive Oxygen Species Formation. PLoS One. 2015;10(6):e0127309.

 

Bai Y, Shang Y, Liu Z, Lu B and Sun Q. Pre-exposure to Fine Particulate Matters may Induce Endotoxin Tolerance in a Mouse Model. Austin J Environ Toxicol. 2015;1(2):1006

 

Bai Y, Wang D, Jiang L, Liu X, Yang G, Geng C, Zhong L, Sun Q*, Chen M*. The Role of Oxidative Stress in Citreoviridin-Induced DNA Damage in Human Liver-Derived HepG2 Cells. Environ Toxicol 30: 530–537, 2015 (*co-corresponding authors)

 

Chen R, Zhao Z, Sun Q, Lin Z, Zhao A, Wang C, Xia Y, Xu X, Kan H. Size-fractionated Particulate Air Pollution and Circulating Biomarkers of Inflammation, Coagulation, and Vasoconstriction in a Panel of Young Adults. Epidemiology. 2015; 26:328-36

 

Zhao J, Liu C; Bai Y; Wang T; Kan H, Sun Q. IKK Inhibition prevents PM2.5-exacerbated cardiac injury in the mice with Type II Diabetes. Journal of Environmental Sciences. 2015;31:98-103

 

Bai Y, and Sun Q. Macrophage recruitment in obese adipose tissue. Obes Rev. 2015;16:127-36.

 

Cui Y, Xie X, Jia F, He J, Li Z, Fu M, Hao H, Liu Y, Liu JZ, Cowan PJ, Zhu H, Sun Q, Liu Z. Ambient fine particulate matter induces apoptosis of endothelial progenitor cells through reactive oxygen species formation. Cell Physiol Biochem. 2015;35:353-63.

 

Long Y, Hong X. Sun Q. Ambient Particulate Matters on Pregnancy and embryo development. Chin J Perinat Med. 2015;18:4-8 (Review, in Chinese)

 

Morishita M, Bard RL, Wang L, Das R, Dvonch JT, Spino C, Mukherjee B, Sun Q, Harkema JR, Rajagopalan S, Brook RD. The characteristics of coarse particulate matter air pollution associated with alterations in blood pressure and heart rate during controlled exposures. J Expo Sci Environ Epidemiol. 2015;25:153-9

 

Li Y, Cai M, Cao L, Qin X, Zheng T, Xu X, Sandvick TM, Hutchinson K, Wold LE, Hu K, Sun Q, Thomas DP, Ren J, He G. Endurance Exercise Accelerates Myocardial Tissue Oxygenation Recovery and Reduces Ischemia Reperfusion Injury in Mice. PLoS One. 2014;9:e114205

 

Liang Y, Fang L, Pan H, Zhang K, Kan H, Brook JR and Sun Q. PM2.5 in Beijing - temporal pattern and its association with influenza. Environ Health. 2014;13:102

 

Liu C, Fonken LK, Wang A, Maiseyeu A, Bai Y, Wang TY, Maurya S, Ko YA, Periasamy M, Dvonch T, Morishita M, Brook RD, Harkema J, Ying Z, Mukherjee B, Sun Q, Nelson RJ, Rajagopalan S. Central IKKβ inhibition prevents air pollution mediated peripheral inflammation and exaggeration of type II diabetes. Part Fibre Toxicol. 2014;30;11:53

 

Rao X, Zhong J, Sun Q. The heterogenic properties of monocytes/macrophages and neutrophils in inflammatory response in diabetes. Life Sci. 2014;116:59-66 (Review)

 

Rao X, Zhong J, Maiseyeu A, Gopalakrishnan B, Villamena FA, Chen LC, Harkema JR, Sun Q*, and Rajagopalan S*. CD36-dependent 7-ketocholesterol Accumulation in Macrophages Mediates Progression of Atherosclerosis in Response to Chronic Air Pollution Exposure. Circ Res. 2014;115:770-780 (*co-corresponding authors)

 

Gorr M, Velten M, Nelin T, Youtz D, Sun Q, and Wold L. Early Life Exposure to Air Pollution Induces Adult Cardiac Dysfunction. Am J Physiol Heart Circ Physiol 2014;307: H1353–H1360

 

Liu C, He X, Hong X, Kang F, Chen S, Wang Q, Chen X, Hu D, Sun Q. Suppression of Placental Metallothionein 1 and Zinc Transporter 1 mRNA Expressions Contributes to Fetal Heart Malformations Caused by Maternal Zinc Deficiency. Cardiovasc Toxicol 2014;14:329–338

 

Liu C, Bai Y, Xu X, Sun L, Wang A, Wang TY, Maurya SK, Periasamy M, Morishita M, Harkema J, Ying Z, Sun Q, Rajagopalan S. Exaggerated effects of particulate matter air pollution in genetic type II diabetes mellitus. Part Fibre Toxicol. 2014;11:27

 

Brook RD, Bard RL, Morishita M, Dvonch JT, Wang L, Yang HY, Spino C, Mukherjee B, Kaplan MJ, Yalavarthi S, Oral EA, Ajluni N, Sun Q, Brook JR, Harkema J, Rajagopalan S. Hemodynamic, Autonomic, and Vascular Effects of Exposure to Coarse Particulate Matter Air Pollution from a Rural Location. Environ Health Perspect. 2014;122:624-630

 

Zhao X , Sun Z, Ruan Y, Yan J, Mukherjee B, Yang F, Duan F, Sun L, Liang R, Lian H, Zhang S, Fang Q, Gu D, Brook J, Sun Q, Dr. Brook R, Rajagopalan S. Fan Z. Personal Black Carbon Exposure Influences Ambulatory Blood Pressure: Air Pollution and Cardio-metabolic Disease (AIRCMD-China) Study. Hypertension. 2014;63:871-7

 

Bai Y, Xu Z, Zhang J, Mao D, Luo C, He H, Liang G, Lu B, Bisesi MS, Sun Q, Xu X, Yang W, Liu Q. Regional impact of climate on Japanese encephalitis in areas located near the Three Gorges Dam. PLoS ONE 2014;9: e84326.

 

Zhong J, Rao X, Braunstein Z, Taylor A, Narula V, Hazey J, Mikami D, Needleman B, Rutsky J, Sun Q, Deiuliis JA, Satoskar AR, Rajagopalan S. T cell costimulation protects obesity-induced adipose inflammation and insulin resistance. Diabetes. 2014;63:1289-302

 

Wagner JG, Allen K, Yang HY, Nan B, Morishita M, Mukherjee B, Dvonch JT, Spino C, Fink GD, Rajagopalan S, Sun Q, Brook RD, Harkema JR. Cardiovascular Depression in Rats Exposed to Inhaled Particulate Matter and Ozone: Effects of Diet-Induced Metabolic Syndrome. Environ Health Perspect 2014;122:27–33

 

Liu C, Xu X, Bai Y, Wang TY, Rao X, Wang A, Sun L, Ying Z, Gushchina L, Maiseyeu A, Sun Q, Harkema JR, Rajagopalan S. Air-Pollution Mediated Susceptibility to Inflammation and Insulin Resistance via CCR2 Dependent and Independent Effects. Environ Health Perspect 2014;122:17–26

 

Ying Z, Xu X, Bai Y, Zhong J, Chen M, Liang Y, Zhao J, Liu D, Morishita M, Sun Q, Spino C, Brook RD, Harkema JR , Rajagopalan S. Long-Term Exposure to Concentrated Ambient PM2.5 Increases Mouse Blood Pressure through Abnormal Activation of the Sympathetic Nervous System: A Role for Hypothalamic Inflammation. Environ Health Perspect 2014;122:79–86

 

Maiseyeu A, Yang HY, Ramanathan G, Yin F, Bard RL, Morishita M, Dvonch JT, Wang L, Spino C, Mukherjee B, Badgeley MA, Barajas-Espinosa A, Sun Q, Harkema J, Rajagopalan S, Araujo JA, Brook RD. No effect of acute exposure to coarse particulate matter air pollution in a rural location on high-density lipoprotein function. Inhal Toxicol. 2014;26:23-9.

 

Sun L, Liu C , Xu X, Ying Y, Maiseyeu A, Wang A, Allen K, Lewandowski RP, Bramble LA, Morishita M, Wagner JG, Dvonch JT, Sun Z, Yan X, Brook RD, Rajagopalan S, Harkema JR, Sun Q*, Fan Z*. Ambient fine particulate matter and ozone exposures induce inflammation in epicardial and perirenal adipose tissues in rats fed a high fructose diet. Part Fibre Toxicol; 2013, 10:43 (*co-corresponding authors)

 

Brook RD, Bard RL, Kaplan MJ, Yalavarthi S, Morishita M, Dvonch JT, Wang L, Yang HY, Spino C, Mukherjee B, Oral EA, Sun Q, Brook JR, Harkema J, Rajagopalan S. The effect of acute exposure to coarse particulate matter air pollution in a rural location on circulating endothelial progenitor cells: results from a randomized controlled study. Inhalation Toxicology 2013;25:587-92

 

Xu X, Jiang SY, Wang TY, Bai Y, Zhong M, Wang A, Lippmann M, Chen LC, Rajagopalan S, Sun Q. Inflammatory Response to Fine Particulate Air Pollution Exposure: Neutrophil versus Monocyte. PLoS ONE 2013; 8(8): e71414

 

Ying Z, Xu X, Sun Q, Rajagopalan S. A Synergic Vascular Effect of Airborne Particle Matter and Nickel in a Mouse Model. Toxicol Sci. 2013;135:72-80

 

Liu MJ, Bao S, Bolin ER, Burris DL, Xu X, Sun Q, Killilea DW, Shen Q, Ziouzenkova O, Belury MA, Failla ML, Knoell DL. Zinc Deficiency Augments Leptin Production and Exacerbates Macrophage Infiltration into Adipose Tissue in Mice Fed a High-Fat Diet. J Nutr. 2013;143:1036-45

 

Mendez R, Zheng Z, Fan Z, Rajagopalan S, Sun Q*, and Zhang K*. Exposure to Fine Airborne Particulate Matter Induces Macrophage Infiltration, Unfolded Protein Response, and Lipid Deposition in White Adipose Tissue. Am J Transl Res 2013;5:224-234 (*co-corresponding authors)

 

Li Y, Cai M, Sun Q, Liu Z, Cardounel AJ, Swartz HM, He G. Hyperoxia and transforming growth factor β1 signaling in the post-ischemic mouse heart. Life Sci. 2013;92:547-554

 

Liu C, Desikan R, Ying Z, Gushchina L, Kampfrath T, Deiuliis J, Wang A, Xu X, Zhong J, Rao X, Sun Q, Maiseyeu A, Parthasarathy S, Rajagopalan S. Effects of a Novel Pharmacologic Inhibitor of Myeloperoxidase in a Mouse Atherosclerosis Model. PLoS ONE 2013;7(12): e50767

 

Sun Z, Mukherjee B, Brook R, Gatts G, Yang F, Fan Z, Brook J, Sun Q, Rajagopalan S. Air-Pollution and Cardiovascular Diseases (AIRCMD): A Prospective Study Investigating the Impact of Air Pollution Exposure and Propensity for Type II Diabetes. Sci Total Environ. 2013;448:72-78

 

Liu C, Ying Z, Harkema J, Sun Q, Rajagopalan S. Epidemiological and Experimental Links between Air Pollution and Type 2 Diabetes. Toxicol Pathol. 2013; 41: 361-373

 

Brook RD, Xu X, Bard RL, Dvonch JT, Morishita M, Kaciroti N, Sun Q, Harkema J, Rajagopalan S. Reduced metabolic insulin sensitivity following sub-acute exposures to low levels of ambient fine particulate matter air pollution. Sci Total Environ. 2013;448:66-71