Professor and Dean's Fellow for Diversity, Equity and Inclusive Excellence
I spent the first 20 years of my career unraveling the molecular-level mechanisms in the central nervous system that give rise to behavioral learning and memory deficits, which are relevant to children and adolescents who live close to sources of environmental pollution. I’ll spend the next 20 years continuing my innovation in discovery as co-architect of the Public Health Exposome framework focused on determining if there are associations between the built, natural, physical and social environment and the disparate health outcomes in vulnerable populations.
Contact
408 Cunz Hall
1841 Neil Ave
Columbus, OH 43210
Email: hood.188@osu.edu
Phone: 614-247-4941
Pronouns: he/him/his
View CV
Website:
Wikipedia Page
Darryl B. Hood, Ph.D. is a nationally recognized environmental public health neurotoxicologist and environmental justice expert at The Ohio State University. After serving on the faculty for more than 20 years at the Meharry-Vanderbilt Alliance, Dr. Hood moved his laboratory in 2013 to Ohio State to continue his innovative work as co-architect of the novel Public Health Exposome framework with big-data-to-knowledge analytics. In Columbus, Dr. Hood has assembled a multidisciplinary, community-based research stakeholder team to address disparate health outcomes in environmental justice census tracts. His work focuses on determining if there are associations between the built, natural, physical and social environment and disparate health outcomes observed in vulnerable populations. The exposome framework is relevant to the disparities documented across the COVID-19 syndemic and in the public health impacts of climate change. Dr. Hood is currently applying the exposome framework and analytics as the principal investigator of the U.S. Environmental Protection Agency STAR “ENVISION” initiative, Co-principal investigator and Ohio State leader of the Columbus Climate Pollution Reduction grant, and co-principal investigator of a second U.S. EPA STAR “FLEETS for ALL” electrification initiative. Dr. Hood also serves on the National Advisory Environmental Health Sciences Council at the National Institute of Environmental Health Sciences, Society of Toxicology leadership council and on two National Academy of Sciences Engineering and Medicine committees.
Dr. Hood's Media
November 2021
Ohio State Office of Outreach and Engagement
https://engage.osu.edu/engaged-scholars-darryl-hood
June 11, 2012
The Washington Times
https://www.scribd.com/document/176620798/Sometimes-environmental-justi…
April 9, 2016
Diversity in Public Health Summit: Homelessness, Giving a Voice to an Underserved Population
Additional Links
http://www.nationwidechildrens.org/perinatal-brain-injury-and-developme…
http://www.toxicology.org/isot/sig/tao/officers.asp
Inhalation Toxicology (prenatal exposure models autism), Developmental neurobiology (somatosensory cortex), Behavioral neurobiology (development of structure-specific paradigms), Environmental and biochemical toxicology (Nitroxides, PAH’s), Dispersion modeling of PAH’s in environmental justice communities, Structural biology, protein structure and function, Environmental-exposure health assessment questionnaire development, Modeling exposures across lifetime using public health exposome approach
- Postdoc, Vanderbilt University School of Medicine, Dept. of Biochemistry and Center in Molecular Toxicology, Biophysics/ Molecular Toxicology, 1990-1994
- Ph.D., East Tennessee State University, James H. Quillen College of Medicine, Biomedical Science/Biochemistry, 1990
- B.S., Johnson C. Smith University, Biology/Chemistry, 1985
Felix AS, Lehman A, Nolan TS, Sealy-Jefferson S, Breathett K, Hood DB, Addison D, Anderson CM, Cené CW, Warren BJ, Jackson RD, Williams KP. Stress, Resilience, and Cardiovascular Disease Risk Among Black Women. Circ Cardiovasc Qual Outcomes. 2019. Apr;12(4): e005284. doi: 10.1161/CIRCOUTCOMES. 118.005284. PMID: 30909729
Cifuentes P, Reichard J, Im W, Smith S, Colen C, Giurgescu C, Williams KP, Gillespie S, Juarez PD, Hood DB. Application of the Public Health Exposome Framework to Estimate Phenotypes of Resilience in a Model Ohio African-American Women's Cohort. J Urban Health. 2019. Mar;96 (Suppl. 1):57-71.
Paul D. Juarez, Mohammad Tabatabai, R. Burciaga Valdez, Darryl B. Hood, Wansoo Im, Charles Mouton, Cynthia Colen, Mohammad Z. Al-Hamdan, Patricia Matthews-Juarez, Maureen Y. Lichtveld, Daniel Sarpong, Aramandla Ramesh, Michael A. Langston, Gary L. Rogers, Charles A. Phillips, John F. Reichard, Macarius M. Donneyong and William Blot.The Effects of Social, Personal, and Behavioral Risk Factors and PM2.5 on Cardio-Metabolic Disparities in a Cohort of Community Health Center Patients. IJERPH, 2020. 17, 3561; doi:10.3390/ijerph17103561
Juarez PD, Hood DB, Rogers GL, Baktash SH, Saxton AM, Matthews-Juarez P, Im W, Cifuentes MP, Phillips CA, Lichtveld MY, Langston MA. A novel approach to analyzing lung cancer mortality disparities: Using the exposome and a graph-theoretical toolchain. Environ Dis 2017; 2: 33-44. PMID: 29152601
Clark, RS, Pellom, ST, Booker, B, Ramesh, A, Zhang, T, SHanker, A, Maguire, M, Juarez, P, Matthews-Juarez, P, Langston, M., Lichtveld, M. and Hood, DB. Validation of research trajectory 1 of an Exposome framework: Exposure to benzo(a)pyrene confers enhanced susceptibility tobacterial infection." Environ Res. Vol. 146, 2016: p173-184. PubMed PMID: 26765097
Langston MA, Levine RS, Kilbourne BJ, Rogers GL, Kershenbaum AD, Baktash SH, Coughlin SS, Saxton AM, Agboto VK, Hood DB, Litchveld MY, Oyana TJ, Matthews-Juarez P, Juarez PD. Scalable combinatorial tools for health disparities research. Int J Environ Res Public Health. 2014 Oct 10;11(10):10419-43. PubMed PMID: 25310540
Juarez PD, Matthews-Juarez P, Hood DB, Im W, Levine RS, Kilbourne BJ, Langston MA, Al-Hamdan MZ, Crosson WL, Estes MG, Estes SM, Agboto VK, Robinson P, Wilson S, Lichtveld MY. The public health exposome: a population-based, exposure science approach to health disparities research. Int J Environ Res Public Health. 2014 Dec;11(12):12866-95. PubMed PMID: 25590101
Hood DB, Nayyar T, Ramesh A, Greenwood M, Inyang F. Modulation in the developmental expression profile of Sp1 subsequent to transplacental exposure of fetal rats to desorbed benzo[a]pyrene following maternal inhalation. Inhal Toxicol. 2000 Jun;12(6):511-35. PubMed PMID: 10880142.
Ramesh A, Greenwood M, Inyang F, Hood DB. Toxicokinetics of inhaled benzo[a]pyrene: plasma and lung bioavailability. Inhal Toxicol. 2001 Jun;13(6):533-55. PubMed PMID: 11445891.
Laknaur A, Foster TL, Bobb LE, Ramesh A, Ladson GM, Hood DB, Al-Hendy A, Thota C. Altered expression of histone deacetylases, inflammatory cytokines and contractile-associated factors in uterine myometrium of Long Evans rats gestationally exposed to benzo(a)pyrene. J. Appl. Toxicol. 2015 PMID: 26358852.
Wu J, Ramesh A, Nayyar T, Hood DB. Assessment of metabolites and AhR and CYP1A1 mRNA expression subsequent to prenatal exposure to inhaled benzo(a)pyrene. Int J Dev Neurosci. 2003 Oct;21(6):333-46. PubMed PMID: 12927582.
Wormley DD, Ramesh A, Hood DB. Environmental contaminant-mixture effects on CNS development, plasticity, and behavior. Toxicol Appl Pharmacol. 2004 May 15;197(1):49-65. PubMed PMID: 15126074.
Wormley DD, Chirwa S, Nayyar T, Wu J, Johnson S, Brown LA, Harris E, Hood DB. Inhaled benzo(a)pyrene impairs long-term potentiation in the F1 generation rat dentate gyrus. Cell Mol Biol (Noisy-le-grand). 2004 Sep;50(6):715-21. PubMed PMID: 15641162.
Hood DB, Woods L, Brown L, Johnson S, Ebner FF. Gestational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure effects on sensory cortex function. Neurotoxicology. 2006 Dec;27(6):1032-42. PubMed PMID: 16839606.
McCallister MM, Li Z, Zhang T, Ramesh A, Clark RS, et al. Revealing Behavioral Learning Deficit Phenotypes Subsequent to in utero Exposure to Benzo(a)pyrene. Toxicological Sciences. 2015 Sept; 13: 1-13. PMID: 26420751
McCallister MM, Maguire M, Ramesh A, Aimin Q, Liu S, Khoshbouei H, Aschner M, Ebner FF, Hood DB. Prenatal exposure to benzo(a)pyrene impairs later-life cortical neuronal function. Neurotoxicology. 2008 Sep;29(5):846-54. PubMed PMID: 18761371; PubMed Central PMCID: PMC2752856.
Ford GD, Ford BD, Steele EC Jr, Gates A, Hood D, Matthews MA, Mirza S, Macleish PR. Analysis of transcriptional profiles and functional clustering of global cerebellar gene expression in PCD3J mice. Biochem Biophys Res Commun. 2008 Dec 12;377(2):556-61. PubMed PMID: 18930027; PubMed Central PMCID: PMC2628286.
Sheng L, Ding X, Ferguson M, McCallister M, Rhoades R, Maguire M, Ramesh A, Aschner M, Campbell D, Levitt P, Hood DB. Prenatal polycyclic aromatic hydrocarbon exposure leads to behavioral deficits and downregulation of receptor tyrosine kinase, MET. Toxicol Sci. 2010 Dec;118(2):625-34. PubMed PMID: 20889680; PubMed Central PMCID: PMC2984527.
Li Z, Chadalapaka G, Ramesh A, Khoshbouei H, Maguire M, Safe S, Rhoades RE, Clark R, Jules G, McCallister M, Aschner M, Hood DB. PAH particles perturb prenatal processes and phenotypes: protection from deficits in object discrimination afforded by dampening of brain oxidoreductase following in utero exposure to inhaled benzo(a)pyrene. Toxicol Sci. 2012 Jan;125(1):233-47. PubMed PMID: 21987461; PubMed Central PMCID: PMC3243744.
Chinonso N. Ogojiaku, JC Allen, Rexford Anson-Dwamena, Kierra S. Barnett, Olorunfemi Adetona, Wansoo Im, Darryl B. Hood. The Health Opportunity Index: Understanding the Input to Disparate Health Outcomes in Vulnerable and High-Risk Census Tracts. Int. J. Environ. Res. Public Health 2020, 17, (in press)
John F. Obrycki, Tyler Serafini, Darryl B. Hood, Chris Alexander, Pam Blais, Nicholas T.
Basta. Using Public Health Data for Soil Pb Hazard Management. Ohio J Public Health Manag. Pract. 2017 Jan 11. doi: 10.1097/PHH.0000000000000488. [Epub ahead of print] PMID: 28079647
Stokes SC, Hood DB, Zokovitch J, Close FT. Blueprint for communicating risk and preventing environmental injustice. J Health Care Poor Underserved. 2010 Feb;21(1):35-52. PubMed PMID: 20173254.
Jiao Y, Bower JK, Im W, Basta N, Obrycki J, Al-Hamdan MZ, Wilder A, Bollinger CE, Zhang T, Hatten L Sr, Hatten J, Hood DB. Int J Environ Res Public Health. 2016 Dec 22;13(1):ijerph13010011. doi:10.3390/ijerph13010011. PMID:26703664
PubMed URL: https://www.ncbi.nlm.nih.gov/myncbi/darryl.hood.1/bibliography/public/